I have set my room up quite differently this year - still placing an emphasis on having a shared space for the whole class, an 'empty' table space for group work (desk groups can also be used), and also pockets for purpose - such as an office where the computers are, a maths area, a literacy area and a creative design (art) area. It will be interesting to see how the layout works and how the children respond to it.
Take a look at the pics,
Classroom January 2013 on PhotoPeach